Table of Contents Table of Contents 2 List of Tables 4 List of Figures 4 Introduction 6 Global Markets Direct Report Coverage 6 Acute Renal Failure (ARF) (Acute Kidney Injury) - Overview 7 Acute Renal Failure (ARF) (Acute Kidney Injury) - Therapeutics Development 8 Pipeline Overview 8 Pipeline by Companies 9 Pipeline by Universities/Institutes 12 Products under Development by Companies 13 Products under Development by Universities/Institutes 15 Acute Renal Failure (ARF) (Acute Kidney Injury) - Therapeutics Assessment 16 Assessment by Target 16 Assessment by Mechanism of Action 18 Assessment by Route of Administration 20 Assessment by Molecule Type 22 Acute Renal Failure (ARF) (Acute Kidney Injury) - Companies Involved in Therapeutics Development 24 A1M Pharma AB 24 Alloksys Life Sciences BV 24 Am-Pharma BV 24 Angion Biomedica Corp 25 Arch Biopartners Inc 25 Cellmid Ltd 26 CFM Pharma Holding BV 26 Cypralis Ltd 27 DURECT Corp 27 Evotec AG 27 Exponential Biotherapies Inc 28 G1 Therapeutics Inc 28 Kringle Pharma Inc 29 Mitotech SA 29 Quark Pharmaceuticals Inc 30 SBI Pharmaceuticals Co Ltd 30 Silver Creek Pharmaceuticals Inc 31 Spherium Biomed SL 31 STATegics Inc 31 Stealth BioTherapeutics Inc 32 Torrent Pharmaceuticals Ltd 32 Xigen SA 33 Acute Renal Failure (ARF) (Acute Kidney Injury) - Drug Profiles 34 (aminolevulinic acid hydrochloride + sodium ferrous citrate) - Drug Profile 34 ANG-4102 - Drug Profile 36 BB-3 - Drug Profile 37 brimapitide - Drug Profile 41 CAB-101 - Drug Profile 47 CC-4066 - Drug Profile 49 cilastatin - Drug Profile 50 Drug for Kidney Diseases - Drug Profile 51 DUR-928 - Drug Profile 52 EA-230 - Drug Profile 57 elamipretide - Drug Profile 59 G-1T100182 - Drug Profile 68 IL-233 - Drug Profile 69 iron sucrose + Sn protoporphyrin - Drug Profile 70 K-1052 - Drug Profile 71 KP-100IT - Drug Profile 72 Metablok - Drug Profile 74 MG-53 - Drug Profile 75 NOXD-21 - Drug Profile 77 NYK-1341 - Drug Profile 78 Plastomitin - Drug Profile 79 QPI-1002 - Drug Profile 80 R-190 - Drug Profile 84 Recombinant Alkaline Phosphatase Enzyme Replacement for Acute Kidney Injury - Drug Profile 85 Recombinant Human Alkaline Phosphatase Replacement for Acute Renal Failure, Hypophosphatasia, Sepsis and Ulcerative Colitis - Drug Profile 86 Recombinant Klotho Replacement for Kidney Disease, Aging, Breast Cancer, Cognitive Impairment and Type 2 Diabetes - Drug Profile 90 Recombinant Peptides to Agonize renalase for Acute Pancreatitis, Acute Kidney Injury and Cisplatin Induced Kidney Injury - Drug Profile 92 Recombinant Protein for Acute Kidney Injury, Acute Radiation Syndrome, Inflammatory Bowel Disease, Ischemic Organ Injury, and Sepsis - Drug Profile 93 RLS-003 - Drug Profile 94 RMC-035 - Drug Profile 95 SGF-1 - Drug Profile 99 Small Molecule to Inhibit HDAC for Acute Kidney Injury - Drug Profile 100 Small Molecule to Inhibit PADI4 for Acute Kidney Injury, Hepatic and Pancreatic Injuries - Drug Profile 101 STSE-15 - Drug Profile 102 SUL-138 - Drug Profile 104 TR

List of Tables Number of Products under Development for Acute Renal Failure (ARF) (Acute Kidney Injury), H1 2018 Number of Products under Development by Companies, H1 2018 Number of Products under Development by Companies, H1 2018 (Contd..1), H1 2018 Number of Products under Development by Universities/Institutes, H1 2018 Products under Development by Companies, H1 2018 Products under Development by Companies, H1 2018 (Contd..1), H1 2018 Products under Development by Universities/Institutes, H1 2018 Number of Products by Stage and Target, H1 2018 Number of Products by Stage and Mechanism of Action, H1 2018 Number of Products by Stage and Route of Administration, H1 2018 Number of Products by Stage and Molecule Type, H1 2018 Acute Renal Failure (ARF) (Acute Kidney Injury) - Pipeline by A1M Pharma AB, H1 2018 Acute Renal Failure (ARF) (Acute Kidney Injury) - Pipeline by Alloksys Life Sciences BV, H1 2018 Acute Renal Failure (ARF) (Acute Kidney Injury) - Pipeline by Am-Pharma BV, H1 2018 Acute Renal Failure (ARF) (Acute Kidney Injury) - Pipeline by Angion Biomedica Corp, H1 2018 Acute Renal Failure (ARF) (Acute Kidney Injury) - Pipeline by Arch Biopartners Inc, H1 2018 Acute Renal Failure (ARF) (Acute Kidney Injury) - Pipeline by Cellmid Ltd, H1 2018 Acute Renal Failure (ARF) (Acute Kidney Injury) - Pipeline by CFM Pharma Holding BV, H1 2018 Acute Renal Failure (ARF) (Acute Kidney Injury) - Pipeline by Cypralis Ltd, H1 2018 Acute Renal Failure (ARF) (Acute Kidney Injury) - Pipeline by DURECT Corp, H1 2018 Acute Renal Failure (ARF) (Acute Kidney Injury) - Pipeline by Evotec AG, H1 2018 Acute Renal Failure (ARF) (Acute Kidney Injury) - Pipeline by Exponential Biotherapies Inc, H1 2018 Acute Renal Failure (ARF) (Acute Kidney Injury) - Pipeline by G1 Therapeutics Inc, H1 2018 Acute Renal Failure (ARF) (Acute Kidney Injury) - Pipeline by Kringle Pharma Inc, H1 2018 Acute Renal Failure (ARF) (Acute Kidney Injury) - Pipeline by Mitotech SA, H1 2018 Acute Renal Failure (ARF) (Acute Kidney Injury) - Pipeline by Quark Pharmaceuticals Inc, H1 2018 Acute Renal Failure (ARF) (Acute Kidney Injury) - Pipeline by SBI Pharmaceuticals Co Ltd, H1 2018 Acute Renal Failure (ARF) (Acute Kidney Injury) - Pipeline by Silver Creek Pharmaceuticals Inc, H1 2018 Acute Renal Failure (ARF) (Acute Kidney Injury) - Pipeline by Spherium Biomed SL, H1 2018 Acute Renal Failure (ARF) (Acute Kidney Injury) - Pipeline by STATegics Inc, H1 2018 Acute Renal Failure (ARF) (Acute Kidney Injury) - Pipeline by Stealth BioTherapeutics Inc, H1 2018 Acute Renal Failure (ARF) (Acute Kidney Injury) - Pipeline by Torrent Pharmaceuticals Ltd, H1 2018 Acute Renal Failure (ARF) (Acute Kidney Injury) - Pipeline by Xigen SA, H1 2018 Acute Renal Failure (ARF) (Acute Kidney Injury) - Dormant Projects, H1 2018 Acute Renal Failure (ARF) (Acute Kidney Injury) - Dormant Projects, H1 2018 (Contd..1), H1 2018 Acute Renal Failure (ARF) (Acute Kidney Injury) - Discontinued Products, H1 2018 List of Figures Nu

A1M Pharma AB Alloksys Life Sciences BV Am-Pharma BV Angion Biomedica Corp Arch Biopartners Inc Cellmid Ltd CFM Pharma Holding BV Cypralis Ltd DURECT Corp Evotec AG Exponential Biotherapies Inc G1 Therapeutics Inc Kringle Pharma Inc Mitotech SA Quark Pharmaceuticals Inc SBI Pharmaceuticals Co Ltd Silver Creek Pharmaceuticals Inc Spherium Biomed SL STATegics Inc Stealth BioTherapeutics Inc Torrent Pharmaceuticals Ltd Xigen SA